| Jogo | Data | Hora | EqCasa | GlC | GlF | EqFora |
|---|---|---|---|---|---|---|
| 6 | 2021-09-11 | 15:30 | P. Ferreira | 0 | 0 | SC Braga |
| 7 | 2021-09-11 | 18:00 | Santa Clara | 0 | 5 | Benfica |
| 9 | 2021-09-11 | 20:30 | Sporting | 1 | 1 | FC Porto |
| 5 | 2021-09-12 | 15:30 | Moreirense | 2 | 2 | FC Famalicão |
| 2 | 2021-09-12 | 18:00 | Boavista | 1 | 1 | Portimonense |
| 4 | 2021-09-12 | 18:00 | Gil Vicente | 2 | 2 | FC Vizela |
| 8 | 2021-09-12 | 20:30 | V. Guimarães | 0 | 0 | Belenenses SAD |
| 3 | 2021-09-13 | 19:00 | Marítimo | 2 | 2 | Arouca |
| 1 | 2021-09-13 | 21:15 | Tondela | 1 | 2 | Estoril Praia |